MicroRNAs and Allergic Diseases
نویسنده
چکیده
microRNAs are a class of small, non-coding RNAs that regulate the expression of a diverse array of genes and pathways, with important roles in disease pathogenesis. Many of these microRNAs are currently under investigation as biomarkers or therapeutic options in a range of diseases. Here, we discuss the role of microRNAs in allergic diseases, allergic asthma, allergic rhinitis and atopic dermatitis as they have been strongly implicated in the pathogenesis of skin inflammation. We outline the history and application of microRNAs for the detection and treatment of allergic diseases in comparison with other diseases, such as cancer and other inflammatory diseases, which may assist the development of diagnostic and therapeutic strategies.
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تاریخ انتشار 2017